Isaac Delke, MD, FACOG
Professor
Department:
Obstetrics and Gynecology – Jacksonville
Business Phone:
(904) 244-5626
Business Email:
isaac.delke@jax.ufl.edu
Accomplishments
Exemplary Teacher Award
2012
·
University of Florida College of Medicine – Jacksonville
20-Year Service Pin
2011
·
University of Florida College of Medicine – Jacksonville
Teaching Profile
Courses Taught
2018
MDC7180 Obs and Gyn Clerkship
Board Certifications
-
Maternal and Fetal MedicineAmerican Board of Obstetrics and Gynecology
-
Obstetrics and GynecologyAmerican Board of Obstetrics and Gynecology
Clinical Profile
Specialties
- Obstetrics and Gynecology
Subspecialties
- Maternal and Fetal Medicine
Areas of Interest
- Amniocentesis
- Eclampsia
- HIV/AIDS in pregnant women and infants
- Hyperemesis gravidarum
- Intrauterine growth restriction
- Nuchal translucency test
- Placenta abruption – definition
- Placenta previa
- Preeclampsia
- Vaginal bleeding in pregnancy
Research Profile
I have extensive experience successfully conducting randomized clinical controlled trials. I am Principal and Co-Principal Investigator for the University of Florida (UF) College of Medicine-Jacksonville site of the Adult AIDS Clinical Trials Group (AACTG), Pediatric AIDS Clinical Trials Group (PACTG), and International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) studies, sponsored by National Institute of Health, 1994-Present. In addition, I have developed national and international clinical guidelines in conjunction with federal agencies. I served as a writing member, USPHS Task Force Recommendations for Use of Antiretroviral Agents during Pregnancy for Maternal Health and Reduction of Perinatal Transmission of HIV; Adult AIDS Clinical Trials Groups (ACTG) – Special Review Committee Member; and member of the Perinatal transmission Committee, Pediatric AIDS Clinical Trials Group (PACTG), Obstetrical Working Group of PACTG; and Women’s Health Committee, Adult AIDS Clinical Trials Group (ACTG). Member, Office of AIDS Research Advisory Council (OARAC), NIH, 2004-2007.
Areas of Interest
- HIV in Pregnancy
- Pregnancy-related maternal death
Publications
Academic Articles
2021
Decrease in Florida’s pregnancy-related mortality from 2009 to 2018: reducing the Black-White disparity.
American journal of obstetrics and gynecology.
225(2):194-196
[DOI] 10.1016/j.ajog.2021.03.040.
[PMID] 33812814.
2018
Pregnancy-Related Deaths, Florida, 1999-2012: Opportunities to Improve Maternal Outcomes.
Maternal and child health journal.
22(2):204-215
[DOI] 10.1007/s10995-017-2392-y.
[PMID] 29119477.
2012
Pregnancy-associated mortality review: the Florida experience.
Seminars in perinatology.
36(1):31-6
[DOI] 10.1053/j.semperi.2011.09.007.
[PMID] 22280863.
2012
Preventability of Pregnancy-Related Deaths From Preeclampsia and Eclampsia in Florida, 1999-2008
American Journal of Obstetrics and Gynecology.
206:S353-S354
2012
Safety and Pharmacokinetics of Nelfinavir During the Second and Third Trimesters of Pregnancy and Postpartum
Hiv Clinical Trials.
13(1):46-59
[DOI] 10.1310/hct1301-46.
2010
Psoas abscess in obstetrics: uncommon condition with common presentations.
Obstetrics and gynecology.
116 Suppl 2:473-474
[DOI] 10.1097/AOG.0b013e3181eae617.
[PMID] 20664422.
2009
Fetal fibronectin as a short-term predictor of preterm birth in symptomatic patients: a meta-analysis.
Obstetrics and gynecology.
114(3):631-640
[DOI] 10.1097/AOG.0b013e3181b47217.
[PMID] 19701045.
2009
Pregnancy-Related Deaths Due To Hemorrhage in Florida, 1999-2007
American Journal of Obstetrics and Gynecology.
201
2007
Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA.
BMC infectious diseases.
7
[PMID] 17584491.
2005
Progestational agents to prevent preterm birth: a meta-analysis of randomized controlled trials.
Obstetrics and gynecology.
105(2):273-9
[PMID] 15684151.
2004
Maternal toxicity and pregnancy complications in human immunodeficiency virus-infected women receiving antiretroviral therapy: PACTG 316.
American journal of obstetrics and gynecology.
190(2):506-16
[PMID] 14981398.
2004
Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332.
The Journal of infectious diseases.
190(12):2167-74
[PMID] 15551216.
2004
The impact of race/ethnicity on mother-to-child HIV transmission in the United States in Pediatric AIDS Clinical Trials Group Protocol 316.
Journal of acquired immune deficiency syndromes (1999).
36(3):800-7
[PMID] 15213563.
2003
Human chorionic gonadotropin in cervicovaginal secretions as a predictor of preterm delivery.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
83(2):151-7
[PMID] 14550589.
2003
Labor induction versus expectant management for postterm pregnancies: a systematic review with meta-analysis.
Obstetrics and gynecology.
101(6):1312-8
[PMID] 12798542.
2003
Special considerations for the HIV-infected patient with preterm labor.
Clinics in perinatology.
30(4):855-74
[PMID] 14714926.
2002
Labor induction with 25 microg versus 50 microg intravaginal misoprostol: a systematic review.
Obstetrics and gynecology.
99(1):145-51
[PMID] 11777525.
2002
The effect of tablet moistening on labor induction with intravaginal misoprostol: a randomized trial.
Obstetrics and gynecology.
99(6):1080-4
[PMID] 12052603.
2001
Systemic inflammatory response syndrome, organ failure, and outcome in critically ill obstetric patients treated in an ICU.
Chest.
120(4):1271-7
[PMID] 11591571.
1999
Cervical ripening and labor induction with a controlled-release dinoprostone vaginal insert: a meta-analysis.
Obstetrics and gynecology.
94(5 Pt 2):878-83
[PMID] 10546777.
1999
Efficacy of maintenance therapy after acute tocolysis: a meta-analysis.
American journal of obstetrics and gynecology.
181(2):484-90
[PMID] 10454704.
1998
Labor induction with prostaglandin E1 misoprostol compared with dinoprostone vaginal insert: a randomized trial.
Obstetrics and gynecology.
91(3):401-5
[PMID] 9491868.
1997
Labor induction with intravaginal misoprostol in term premature rupture of membranes: a randomized study.
Obstetrics and gynecology.
89(6):909-12
[PMID] 9170463.
1997
Misoprostol for cervical ripening and labor induction: a meta-analysis.
Obstetrics and gynecology.
89(4):633-42
[PMID] 9083326.
1997
Randomized trial of two doses of the prostaglandin E1 analog misoprostol for labor induction.
American journal of obstetrics and gynecology.
177(2):364-9; discussion 369
[PMID] 9290452.
1996
Use of misoprostol (prostaglandin E1 methyl analogue) to expedite delivery in severe preeclampsia remote from term.
The Journal of maternal-fetal medicine.
5(1):39-40
[PMID] 8796765.
1995
Calcium supplementation in mild preeclampsia remote from term: a randomized double-blind clinical trial.
Obstetrics and gynecology.
85(6):915-8
[PMID] 7770260.
1995
Predicting fetal lung maturity by visual assessment of amniotic fluid turbidity: comparison with fluorescence polarization assay.
Southern medical journal.
88(10):1031-3
[PMID] 7481958.
1995
Pyelonephritis in pregnancy: once-a-day ceftriaxone versus multiple doses of cefazolin. A randomized, double-blind trial.
American journal of obstetrics and gynecology.
172(1 Pt 1):129-33
[PMID] 7847521.
1994
Cervical ripening in women with previous cesarean deliveries.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
47(1):17-21
[PMID] 7813746.
1993
Labor induction with the prostaglandin E1 methyl analogue misoprostol versus oxytocin: a randomized trial.
Obstetrics and gynecology.
81(3):332-6
[PMID] 8437780.
1981
Abnormal cervical cytology in adolescents.
The Journal of pediatrics.
98(6):985-7
[PMID] 7229807.
Grants
Dec 2012
– Nov 2017
Subcontract Under NICHD Prime Contract No. HHSN275201300003C, NICHD International and Domestic Pediatric and Maternal HIV Studies Coordinating Center, Westat ID-6101-S038.
Role: Project Manager
Funding: WESTAT INC
via NATL INST OF HLTH
Education
Maternal and Fetal Medicine Fellowship
1982
·
State University of New York Health Science Center at Brooklyn
Obstetrics and Gynecology Residency
1979
·
Brookdale University Hospital Medical Center
Doctor of Medicine
1971
·
Haile Sellassie I University
Contact Details
Phones:
- Business:
- (904) 244-5626
Emails:
- Business:
- isaac.delke@jax.ufl.edu
Administrative Assistant:
Addresses:
- Business Mailing:
-
653-1 W 8TH ST
OB/GYN
JACKSONVILLE FL 322096511 - Business Street:
-
COLLEGE OF MEDICINE – JACKSONVILLE
653-1 W 8TH ST
DEPARTMENT OF OB/GYN
JACKSONVILLE FL 322096511